Validation Data Gallery
Tested Applications
| Positive WB detected in | HEK-293 cells | 
Recommended dilution
| Application | Dilution | 
|---|---|
| Western Blot (WB) | WB : 1:500-1:2000 | 
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Published Applications
| KD/KO | See 2 publications below | 
| WB | See 10 publications below | 
| IHC | See 1 publications below | 
| IP | See 2 publications below | 
Product Information
11338-1-AP targets SUV39H2 in WB, IHC, IP, ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat | 
| Cited Reactivity | human, mouse | 
| Host / Isotype | Rabbit / IgG | 
| Class | Polyclonal | 
| Type | Antibody | 
| Immunogen | 
                                             CatNo: Ag1882 Product name: Recombinant human SUV39H2 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 44-350 aa of BC007754 Sequence: VKKGKAITPKDNNKTLKPAIAEYIVKKAKQRIALQRWQDELNRRKNHKGMIFVENTVDLEGPPSDFYYINEYKPAPGISLVNEATFGCSCTDCFFQKCCPAEAGVLLAYNKNQQIKIPPGTPIYECNSRCQCGPDCPNRIVQKGTQYSLCIFRTSNGRGWGVKTLVKIKRMSFVMEYVGEVITSEEAERRGQFYDNKGITYLFDLDYESDEFTVDAARYGNVSHFVNHSCDPNLQVFNVFIDNLDTRLPRIALFSTRTINAGEELTFDYQMKGSGDISSDSIDHSPAKKRVRTVCKCGAVTCRGYLN 相同性解析による交差性が予測される生物種 | 
                                    
| Full Name | suppressor of variegation 3-9 homolog 2 (Drosophila) | 
| Calculated molecular weight | 53 kDa | 
| Observed molecular weight | 53 kDa | 
| GenBank accession number | BC007754 | 
| Gene Symbol | SUV39H2 | 
| Gene ID (NCBI) | 79723 | 
| RRID | AB_2196730 | 
| Conjugate | Unconjugated | 
| Form | |
| Form | Liquid | 
| Purification Method | Antigen affinity purification | 
| UNIPROT ID | Q9H5I1 | 
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol{{ptg:BufferTemp}}7.3 | 
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. | 
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for SUV39H2 antibody 11338-1-AP | Download protocol | 
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols | 
Publications
| Species | Application | Title | 
|---|---|---|
Mol Cell Requirements for establishment and epigenetic stability of mammalian heterochromatin
  | ||
Nucleic Acids Res ATM, KAP1 and the Epstein-Barr virus polymerase processivity factor direct traffic at the intersection of transcription and replication | ||
Hepatology The histone methyltransferase Suv39h2 contributes to nonalcoholic steatohepatitis in mice.
  | ||
Cell Death Differ Lysine methylation of PPP1CA by the methyltransferase SUV39H2 disrupts TFEB-dependent autophagy and promotes intervertebral disc degeneration | ||
Nucleic Acids Res DICER regulates the expression of major satellite repeat transcripts and meiotic chromosome segregation during spermatogenesis. | ||
Nucleic Acids Res Alternative splicing regulates the expression of G9A and SUV39H2 methyltransferases, and dramatically changes SUV39H2 functions. | 
