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Validation Data Gallery

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  • Immunohistochemistry (IHC) staining of mouse kidney tissue using SUCNR1 Polyclonal antibody (31987-1-AP)

    IHC staining of mouse kidney using 31987-1-AP

    Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 31987-1-AP (SUCNR1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • Immunohistochemistry (IHC) staining of mouse liver tissue using SUCNR1 Polyclonal antibody (31987-1-AP)

    IHC staining of mouse liver using 31987-1-AP

    Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 31987-1-AP (SUCNR1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

［PR］まずは試したいあなたに。トライアルサイズも特別価格 >>『PRIME BUY抗体特割キャンペーン（4/21～）』

SUCNR1 Polyclonal antibody

SUCNR1 Polyclonal Antibody for IHC, ELISA
Cat No. 31987-1-AP

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

IHC, ELISA

Synonyms

Succinate receptor 1, P2Y purinoceptor 1-like, P2Y purinoceptor 1 like, G-protein coupled receptor 91, GPR91

Formulation:  PBS and Azide
PBS and Azide
Conjugate:  Unconjugated
Unconjugated
Size/Concentration: 

-/ -

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テクニカルサポートまたはご購入後1年間の交換／補填対応を承ります。詳細はこちらをご覧ください。

Tested Applications

Positive IHC detected inmouse kidney tissue, mouse liver tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

ApplicationDilution
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

31987-1-AP targets SUCNR1 in IHC, ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen SUCNR1 fusion protein Ag34053 相同性解析による交差性が予測される生物種
Full Name succinate receptor 1
GenBank accession numberBC030948
Gene Symbol SUCNR1
Gene ID (NCBI) 56670
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity Purification
UNIPROT IDQ9BXA5
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

SUCNR1 (Succinate Receptor 1), also known as GPR91, belongs to the family of G protein-coupled receptors (GPCRs) (PMID: 26808164). SUCNR1 has been identified as a receptor for the metabolite succinate, which functions as a metabolic stress signal in various tissues including the liver, kidney, adipose tissue, and retina (PMID: 29968758). SUCNR1 is crucial in linking metabolic stress, inflammation, and energy homeostasis. It mediates signaling through Gq/GNAQ or Gi/GNAI second messengers depending on the cell type and regulated processes.

Protocols

Product Specific Protocols
IHC protocol for SUCNR1 antibody 31987-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols