Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
11350-1-PBS targets SRCRB4D in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag1884 Product name: Recombinant human SRCRB4D protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-190 aa of BC015651 Sequence: MTGTLRTRAWPAAKRAAGLRWALRDEARLSDCFHLGWGQHNCGHHEDAGALCAGEADSEGPEELGLQVQQDGSETTRVPTPRPRDGHLRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLCQPS 相同性解析による交差性が予測される生物種 |
| Full Name | scavenger receptor cysteine rich domain containing, group B (4 domains) |
| Calculated molecular weight | 61 kDa |
| Observed molecular weight | 70 kDa |
| GenBank accession number | BC015651 |
| Gene Symbol | SRCRB4D |
| Gene ID (NCBI) | 136853 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q8WTU2 |
| Storage Buffer | PBS only{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
SRCRB4D (also known as SSC4D or S4D-SRCRB) is a soluble, secreted pattern-recognition receptor belonging to the scavenger receptor cysteine-rich (SRCR) superfamily, characterized by four group B SRCR domains. It is broadly expressed in epithelial cells of the kidney, placenta, liver, intestine, and lung, and functions as an innate immune sensor capable of binding diverse bacteria and protozoan parasites, thereby enhancing phagocytosis by monocytes.