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  • KD/KO Validated

SNRPB Polyclonal antibody

SNRPB Polyclonal Antibody for WB, IHC, ELISA
Cat No. 16807-1-AP

Host / Isotype

Rabbit / IgG

Reactivity

human and More (1)

Applications

WB, IHC, IP, ELISA

Sm protein B/B, Sm protein B/B', Small nuclear ribonucleoprotein associated proteins B and B', Small nuclear ribonucleoprotein-associated proteins B and B', SmB/B

Formulation:  PBS and Azide
PBS and Azide
Conjugate:  Unconjugated
Unconjugated
Size/Concentration: 

-/ -


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国内在庫・納期について

約2万点のプロテインテック製品をコスモバイオ社物流センター(国内)に在庫しています。国内在庫の有無はコスモバイオ社ホームページの「品番検索」でカタログ番号を検索して確認できます。


保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換/補填対応を承ります。詳細はこちらをご覧ください。


Tested Applications

Positive WB detected inJurkat cells, K-562 cells
Positive IHC detected inhuman cervical cancer tissue, human liver cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
Immunohistochemistry (IHC)IHC : 1:20-1:200
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

16807-1-AP targets SNRPB in WB, IHC, IP, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Cited Reactivityhuman, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen SNRPB fusion protein Ag10298 相同性解析による交差性が予測される生物種
Full Name small nuclear ribonucleoprotein polypeptides B and B1
Calculated molecular weight234aa,25 kDa; 285aa,30 kDa
Observed molecular weight 25-30 kDa
GenBank accession numberBC003530
Gene Symbol SNRPB
Gene ID (NCBI) 6628
RRIDAB_2878319
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP14678
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol{{ptg:BufferTemp}}7.3
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

SNRPB (Small Nuclear Ribonucleoprotein Polypeptides B and B1) is a core component of the spliceosome, a complex molecular machine that plays a critical role in pre-mRNA splicing. This process is essential for the removal of introns and the joining of exons to produce mature mRNA molecules.

Protocols

Product Specific Protocols
WB protocol for SNRPB antibody 16807-1-APDownload protocol
IHC protocol for SNRPB antibody 16807-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB,IP

Elife

Type I and II PRMTs inversely regulate post-transcriptional intron detention through Sm and CHTOP methylation.

Authors - Maxim I Maron
humanIHC

Cell Death Dis

SNRPB promotes the tumorigenic potential of NSCLC in part by regulating RAB26.

Authors - Nianli Liu
  • KO Validated
humanWB,IHC

Oncogene

The splicing factor SNRPB promotes ovarian cancer progression through regulating aberrant exon skipping of POLA1 and BRCA2

Authors - Yingwei Li
  • KD Validated
mouse,humanWB,IHC

Aging (Albany NY)

SNRPB promotes the progression of hepatocellular carcinoma via regulating cell cycle, oxidative stress, and ferroptosis

Authors - Xiaoyan Wang
humanIHC

Ann Med

SNRPB and CEP290, predicting the prognosis of diffuse large B cell lymphoma and associated with tumour immune microenvironment

Authors - Jing Tang
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