SMPD2 Polyclonal antibody

SMPD2 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 15239-1-AP

Synonyms

Lyso PAF PLC, N SMase, Neutral sphingomyelinase, NSMASE, NSMASE1, SMPD2



Tested Applications

Positive WB detected inmouse liver tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
Sample-dependent, check data in validation data gallery

Product Information

15239-1-AP targets SMPD2 in WB, ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen SMPD2 fusion protein Ag7367 相同性解析による交差性が予測される生物種
Full Name sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
Calculated molecular weight 48 kDa
Observed molecular weight48 kDa
GenBank accession numberBC000038
Gene symbol SMPD2
Gene ID (NCBI) 6610
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

SMPD2, Sphingomyelin phosphodiesterase 2, is also named as Lyso-platelet-activating factor-phospholipase C and neutral sphingomyelinase (nSMase). It is involved in the sphingolipid metabolism pathway, which can catalyze the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Smpd2/Smpd3 double-mutant mice were found to have severe retardation of late embryonic and postnatal growth and delayed puberty, belonging to hypothalamus-induced combined pituitary hormone deficiency (PubMed: 15764706).

Protocols

Product Specific Protocols
WB protocol for SMPD2 antibody 15239-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols