Validation Data Gallery
Tested Applications
| Positive IHC detected in | mouse brain tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
Recommended dilution
| Application | Dilution |
|---|---|
| Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
21508-1-AP targets SLITRK2 in IHC, ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag15993 Product name: Recombinant human SLITRK2 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 643-830 aa of BC113012 Sequence: VLKRRKGVPSVPRNTNNLDVSSFQLQYGSYNTETHDKTDGHVYNYIPPPVGQMCQNPIYMQKEGDPVAYYRNLQEFSYSNLEEKKEEPATPAYTISATELLEKQATPREPELLYQNIAERVKELPSAGLVHYNFCTLPKRQFAPSYESRRQNQDRINKTVLYGTPRKCFVGQSKPNHPLLQAKPQSEP 相同性解析による交差性が予測される生物種 |
| Full Name | SLIT and NTRK-like family, member 2 |
| Calculated molecular weight | 845 aa, 95 kDa |
| GenBank accession number | BC113012 |
| Gene Symbol | SLITRK2 |
| Gene ID (NCBI) | 84631 |
| RRID | AB_3742039 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q9H156 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
SLITRK2 is a 845 amino acid single-pass transmembrane protein and is expressed at postsynaptic neurons, which plays a important role in regulating neurite outgrowth and excitatory synapse maintenance (PMID: 35840571). It has been reported that SLITRK2 deficiency could lead to abnormal neural network activity, vestibular function, synaptic integrity, and serotonergic function (PMID: 35789858).
Protocols
| Product Specific Protocols | |
|---|---|
| IHC protocol for SLITRK2 antibody 21508-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |