Validation Data Gallery
Tested Applications
| Positive WB detected in | mouse kidney tissue, human kidney tissue |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:500-1:2000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
87757-1-RR targets SLC22A3 in WB, ELISA applications and shows reactivity with human, mouse samples.
| Tested Reactivity | human, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen |
Peptide 相同性解析による交差性が予測される生物種 |
| Full Name | solute carrier family 22 (extraneuronal monoamine transporter), member 3 |
| Calculated molecular weight | 61KD |
| Observed molecular weight | 61 kDa |
| GenBank accession number | NM_021977 |
| Gene Symbol | SLC22A3 |
| Gene ID (NCBI) | 6581 |
| RRID | AB_3745734 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | O75751 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
Solute carrier family 22 member 3 (SLC22A3) is also named Extraneuronal monoamine transporter (EMT) and Organic cation transporter 3 (OCT3). It belongs to the SLC22 transporter family. SLC22A3 is a high-capacity, low-affinity transporter for the neurotransmitters norepinephrine, epinephrine, dopamine, serotonin, and histamine. SLC22A3 plays important roles in interorgan and interorganism small-molecule communication, and also regulates local and overall homeostasis in the body (PMID: 37626799). OCT3 is more widely expressed than OCT1 and OCT2. OCT3 expression is widespread and can be found in the skeletal muscle, heart, brain, placenta, cornea, retina, iris, liver, kidney, and vascular endothelial cells (PMID: 29309257, PMID: 2169772).
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for SLC22A3 antibody 87757-1-RR | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |