Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
14152-1-PBS targets SLA2 in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag5334 Product name: Recombinant human SLA2 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-261 aa of BC042041 Sequence: MGSLPSRRKSLPSPSLSSSVQGQGPVTMEAERSKATAVALGSFPAGGPAELSLRLGEPLTIVSEDGDWWTVLSEVSGREYNIPSVHVAKVSHGWLYEGLSREKAEELLLLPGNPGGAFLIRESQTRRGSYSLSVRLSRPASWDRIRHYRIHCLDNGWLYISPRLTFPSLQALVDHYSELADDICCLLKEPCVLQRAGPLPGKDIPLPVTVQRTPLNWKELDSSLLFSEAATGEESLLSEGLRESLSFYISLNDEAVSLDDA 相同性解析による交差性が予測される生物種 |
| Full Name | Src-like-adaptor 2 |
| Calculated molecular weight | 261 aa, 29 kDa |
| Observed molecular weight | 28-30 kDa |
| GenBank accession number | BC042041 |
| Gene Symbol | SLA2 |
| Gene ID (NCBI) | 84174 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q9H6Q3 |
| Storage Buffer | PBS only{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
SLA2 is an adapter protein, which negatively regulates T-cell receptor (TCR) signaling. It Inhibits T-cell antigen-receptor-induced activation of nuclear factor of activated T-cells and may act by linking signaling proteins such as ZAP70 with CBL, leading to a CBL-dependent degradation of signaling proteins (PMID: 11696592).