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Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
60032-1-Ig targets RUVBL1 in ELISA applications and shows reactivity with human, mouse samples.
| Tested Reactivity | human, mouse |
| Host / Isotype | Mouse / IgM |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | RUVBL1 fusion protein Ag0281 相同性解析による交差性が予測される生物種 |
| Full Name | RuvB-like 1 (E. coli) |
| Calculated molecular weight | 456 aa, 50 kDa |
| Observed molecular weight | 50 kDa |
| GenBank accession number | BC002993 |
| Gene Symbol | RUVBL1 |
| Gene ID (NCBI) | 8607 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Caprylic acid/ammonium sulfate precipitation |
| UNIPROT ID | Q9Y265 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
RUVBL1, also named as TIP49 and NMP238, consists of 456 amino acids (50 kDa) and interacts with TATA-binding protein (TBP), which is a central component for transcriptional regulation by forming complexes with various transcription regulators. RUVBL1 is a component of a large nuclear protein complex, possibly the RNA polymerase II holoenzyme. RUVBL1 is also highly homologous to RuvB proteins that function as a DNA helicase tpromote branch migration of the Holliday junction. This antibody is a mouse monoclonal antibody to human RUVBL1.