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Validation Data Gallery

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  • Flow cytometry (FC) experiment of human PBMCs using Anti-Human Prion protein PrP/CD230 Rabbit Recombin (98414-4-RR)

    FC experiment of human PBMCs using 98414-4-RR (same clone as 98414-4-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human Prion protein PrP/CD230 Rabbit RecAb (98414-4-RR, Clone: 243104D11) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with CoraLite® Plus 647 Anti-Human CD14. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98414-4-PBS in a different storage buffer formulation.

  • Flow cytometry (FC) experiment of human PBMCs using Anti-Human Prion protein PrP/CD230 Rabbit Recombin (98414-4-RR)

    FC experiment of human PBMCs using 98414-4-RR (same clone as 98414-4-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human Prion protein PrP/CD230 Rabbit RecAb (98414-4-RR, Clone: 243104D11) (red) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98414-4-PBS in a different storage buffer formulation.

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Anti-Human Prion protein PrP/CD230 Rabbit Recombinant Antibody, PBS Only

Prion protein PrP/CD230 Uni-rAbTM Recombinant Antibody for FC
Cat No. 98414-4-PBS
Clone No.243104D11

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

Synonyms

Prion protein PrP, PRNP, PrP, Alternative prion protein, AltPrP

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

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テクニカルサポートまたはご購入後1年間の交換／補填対応を承ります。詳細はこちらをご覧ください。

Tested Applications

Recommended dilution

ApplicationDilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

98414-4-PBS targets Prion protein PrP/CD230 in FC applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen Prion protein PrP/CD230 fusion protein Eg3359 相同性解析による交差性が予測される生物種
Full Name prion protein
GenBank accession numberBC012844
Gene Symbol PrP
Gene ID (NCBI) 5621
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP04156
Storage Buffer PBS only{{ptg:BufferTemp}}7.3
Storage ConditionsStore at -80°C.

Background Information

The major prion protein (PrP), also known as CD230, is encoded by the prion protein-encoding gene (PRNP). PrP is widely expressed in a variety of tissues and is abundant in the nervous system and participates in neuronal growth and survival. PrP expression is strongly associated with immune infiltrating cells, immunosuppressive cell infiltration and immune checkpoint molecules. PrP is an immune-related prognostic marker that holds promise for predicting outcomes related to colorectal cancer immunotherapy.