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Phospho-eEF2K (Thr57) Recombinant antibody

Phospho-eEF2K (Thr57) Uni-rAbTM Recombinant Antibody for WB, ELISA
Cat No. 80351-2-RR
Clone No.250222A6

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

EEF2K, Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase, EC:2.7.11.20, eEF 2 kinase, eEF 2K

Formulation:  PBS and Azide
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Unconjugated
Size/Concentration: 

-/ -


ご購入について

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国内在庫・納期について

約2万点のプロテインテック製品をコスモバイオ社物流センター(国内)に在庫しています。国内在庫の有無はコスモバイオ社ホームページの「品番検索」でカタログ番号を検索して確認できます。


保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換/補填対応を承ります。詳細はこちらをご覧ください。


Tested Applications

Positive WB detected inHeLa cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:4000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

80351-2-RR targets Phospho-eEF2K (Thr57) in WB, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen Peptide 相同性解析による交差性が予測される生物種
Full Name eukaryotic elongation factor-2 kinase
Calculated molecular weight 725 aa, 100 kDa
Observed molecular weight100 kDa
GenBank accession numberBC032665
Gene Symbol EEF2K
Gene ID (NCBI) 29904
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDO00418
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol{{ptg:BufferTemp}}7.3
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

Eukaryotic elongation factor‐2 kinase (eEF2K), well‐known to be a Ca2+ calmodulin (CaM)‐dependent kinase, is overexpressed in several types of malignancies, most notably Triple negative breast cancer (TNBC). Increasing evidence indicates that eEF2K may modulate the expression of some apoptotic proteins such as XIAP, c‐FLIPL, Bcl‐XL, PI3KCI and p70S6K to inhibit apoptotic process in cancer. On the other hand, it may regulate autophagy involved in AMPK, mTORC1 and ULK1, thereby promoting cancer cell survival. (PMID: 29094413)

Protocols

Product Specific Protocols
WB protocol for Phospho-eEF2K (Thr57) antibody 80351-2-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols
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