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Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
87149-1-PBS targets Phospho-Vimentin (Ser56) in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen |
Peptide 相同性解析による交差性が予測される生物種 |
| Full Name | vimentin |
| Calculated molecular weight | 54 kDa |
| Observed molecular weight | 57 kDa |
| GenBank accession number | NM_003380 |
| Gene Symbol | VIM |
| Gene ID (NCBI) | 7431 |
| ENSEMBL Gene ID | ENSG00000026025 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | P08670 |
| Storage Buffer | PBS only{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
Vimentin, also named as VIM, belongs to the intermediate filament family. Phospho-Vimentin (Ser56) is a phosphorylated form of the intermediate filament protein Vimentin that plays a significant role in regulating cellular functions such as smooth muscle contraction, cell migration, and mitosis. Phosphorylation of Vimentin at Ser-56 has been found to regulate vimentin depolymerization and the spatial reorientation of vimentin filaments, which modulates intercellular force transmission and contraction in smooth muscle. (PMID: 27457922)