Validation Data Gallery
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Tested Applications
| Positive WB detected in | mouse brain tissue, λ phosphatase treated mouse brain tissue |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:5000-1:50000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
87647-3-RR targets Phospho-CRMP2 (Thr514) in WB, ELISA applications and shows reactivity with human, mouse samples.
| Tested Reactivity | human, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen |
Peptide 相同性解析による交差性が予測される生物種 |
| Full Name | dihydropyrimidinase-like 2 |
| Calculated molecular weight | 62 kDa |
| Observed molecular weight | 60-80 kDa |
| GenBank accession number | NM_001386 |
| Gene Symbol | CRMP2 |
| Gene ID (NCBI) | 1808 |
| RRID | AB_3745674 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | Q16555 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
Dihydropyrimidinase-like 2 (Dpysl2), a protein involved in neuronal differentiation and axonal guidance is found altered in various nervous system diseases. It is also named as CRMP2, ULIP2 and belongs to hydantoinase/dihydropyrimidinase subfamily. Phospho-CRMP2 (Thr514) refers to the phosphorylated form of Collapsin Response Mediator Protein 2 (CRMP2) at threonine residue 514. CRMP2 is a cytosolic phosphoprotein highly expressed in the nervous system that regulates microtubule dynamics, axonal growth, and neuronal polarity. (PMID: 27609071)
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for Phospho-CRMP2 (Thr514) antibody 87647-3-RR | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |