Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Published Applications
| KD/KO | See 3 publications below |
| WB | See 6 publications below |
| IHC | See 2 publications below |
| IF | See 2 publications below |
| IP | See 1 publications below |
| CoIP | See 3 publications below |
| ChIP | See 2 publications below |
Product Information
51043-1-AP targets PROX1 in WB, IHC, IF, IP, CoIP, ChIP, ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human, mouse, hamster |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag0457 Product name: Recombinant human PROX1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 546-736 aa of BC024201 Sequence: TAEGLSLSLIKSECGDLQDMSEISPYSGSAMQEGLSPNHLKKAKLMFFYTRYPSSNMLKTYFSDVKFNRCITSQLIKWFSNFREFYYIQMEKYARQAINDGVTSTEELSITRDCELYRALNMHYNKANDFEVPERFLEVAQITLREFFNAIIAGKDVDPSWKKAIYKVICKLDSEVPEIFKSPNCLQELLH 相同性解析による交差性が予測される生物種 |
| Full Name | prospero homeobox 1 |
| Calculated molecular weight | 737 aa, 83 kDa |
| Observed molecular weight | 90 kDa |
| GenBank accession number | BC024201 |
| Gene Symbol | PROX1 |
| Gene ID (NCBI) | 5629 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q92786 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -20°C. Aliquoting is unnecessary for -20oC storage. |
Background Information
PROX1, Prospero homeobox protein 1, belongs to the Prospero homeobox family and contain a Prospero-type homeobox DNA-binding domain. PROX1 plays a fundamental role in early development of CNS and regulated the expression of gene and development of postmitotic undifferentiated young neuron. Also PROX1 is a specific and required regulator of the development of the lymphatic system. This is a rabbit polyclonal antibody raised against part of C-terminal chain of human PROX1.
Publications
| Species | Application | Title |
|---|---|---|
Genes Dev The homeobox protein Prox1 is a negative modulator of ERR{alpha}/PGC-1{alpha} bioenergetic functions.
| ||
Nat Commun An HDAC3-PROX1 corepressor module acts on HNF4α to control hepatic triglycerides. | ||
PLoS Genet Genomic convergence among ERRα, PROX1, and BMAL1 in the control of metabolic clock outputs.
| ||
Nucleic Acids Res Prospero-related homeobox 1 (Prox1) functions as a novel modulator of retinoic acid-related orphan receptors α- and γ-mediated transactivation.
| ||
Am J Pathol Lymphotoxins Promote the Progression of Human Lymphatic Malformation by Enhancing Lymphatic Endothelial Cell Proliferation. | ||
PLoS One Impact of an Altered PROX1 Expression on Clinicopathology, Prognosis and Progression in Renal Cell Carcinoma. |
