Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
33683-1-PBS targets PLCB4 in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag38268 Product name: Recombinant human PLCB4 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 900-1110 aa of NM_182797.2 Sequence: ALASGVEAKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKEHSTMQKLHCTQVDKIVAQYDKEKSTHEKILEKAMKKKGGSNCLEMKKETEIKIQTLTSDHKSKVKEIVAQHTKEWSEMINTHSAEEQEIRDLHLSQQCELLKKLLINAHEQQTQQLKLSHDRESKEMRAHQAKISMENSKAISQDKSIKNKAERERRVREL 相同性解析による交差性が予測される生物種 |
| Full Name | phospholipase C, beta 4 |
| Calculated molecular weight | 134 kDa，1175aa |
| Observed molecular weight | 134 kDa |
| GenBank accession number | NM_182797.2 |
| Gene Symbol | PLCB4 |
| Gene ID (NCBI) | 5332 |
| RRID | AB_3743049 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Antigen affinity Purification |
| UNIPROT ID | Q15147 |
| Storage Buffer | PBS only{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
Phospholipase C beta 4 (PLCB4) is a direct effector of the endothelin receptor signaling pathway that plays an essential role in lower jaw and middle ear structures development (PMID: 35284927). Additionally, PLCB4 has an critical role in osteosarcoma progression and may serve as a novel diagnostic or therapeutic target in pediatric patients with acute myeloid leukemia (PMID: 39987366; 31788080).