Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
21169-1-PBS targets PITPNM2/NIR3 in IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.
| Tested Reactivity | human, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag15385 Product name: Recombinant human PITPNM2 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 233-328 aa of BC141813 Sequence: EWYGLSMENIRELEKEAQLMLSRKMAQFNEDGEEATELVKHEAVSDQTSGEPPEPSSSNGEPLVGRGLKKQWSTSSKSSRSSKRGASPSRHSISEW 相同性解析による交差性が予測される生物種 |
| Full Name | phosphatidylinositol transfer protein, membrane-associated 2 |
| Calculated molecular weight | 1349 aa, 149 kDa |
| GenBank accession number | BC141813 |
| Gene Symbol | PITPNM2 |
| Gene ID (NCBI) | 57605 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q9BZ72 |
| Storage Buffer | PBS only{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
PITPNM2, also known as NIR3, belongs to a family of membrane-associated phosphatidylinositol transfer domain-containing proteins that share homology with the Drosophila retinal degeneration B (rdgB) protein(PMID: 15627748). PITPNM2/NIR3 promotes both TCRβ selection and positive selection in thymocytes. PITPNM2/NIR3 is required for PIP2 replenishment and TCR-induced calcium signaling in response to weak TCR stimulation(PMID: 36581712).