Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
18279-1-PBS targets PCDHGA1 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | PCDHGA1 fusion protein Ag13107 相同性解析による交差性が予測される生物種 |
| Full Name | protocadherin gamma subfamily A, 1 |
| Calculated molecular weight | 823aa,90 kDa; 931aa,101 kDa |
| Observed molecular weight | 113 kDa |
| GenBank accession number | BC112082 |
| Gene Symbol | PCDHGA1 |
| Gene ID (NCBI) | 56114 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q9Y5H4 |
| Storage Buffer | PBS only , pH 7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
Protocadherins, which constitute the largest subgroup within the cadherin superfamily, are predominantly expressed in the nervous system and are probably involved in the regulation of neuronal recognition and connectivity (PMID: 17936607; 12231349; 17133224). The protocadherin subfamily can be further subdivided into three groups: the clustered protocadherins, comprising α-, β- and γ-protocadherins; δ-protocadherins; and others, many of which are solitary (PMID: 17133224). PCDHGA1 (protocadherin gamma subfamily A1) is a potential calcium-dependent cell-adhesion protein. It may be involved in establishing and maintaining specific neuronal connections in the brain. PCDHGA1 has four glycosylation sites.