OSMR Monoclonal antibody
OSMR Monoclonal Antibody for ELISA
Host / Isotype
Mouse / IgG1
Reactivity
human
Applications
ELISA
Conjugate
Unconjugated
CloneNo.
4B11D4
Cat no : 60071-1-Ig
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| Sample-dependent, check data in validation data gallery | |
Product Information
60071-1-Ig targets OSMR in ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | OSMR fusion protein Ag1426 相同性解析による交差性が予測される生物種 |
| Full Name | oncostatin M receptor |
| Calculated molecular weight | 110 kDa |
| Observed molecular weight | 120 kDa |
| GenBank accession number | BC010943 |
| Gene symbol | OSMR |
| Gene ID (NCBI) | 9180 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein G purification |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
Oncostatin M (OSM) is a member of interleukin-6 family cytokines that modulates proliferation and differentiation in numerous cells (PMID: 22982441). OSM signals via a receptor complex comprising gp130 and the OSMR (also refered to as OSMRβ) (PMID: 8999038). OSMR is a single-pass membrane protein which belongs to the type I cytokine receptor family. OSMR mRNA is expressed at relatively high levels in all neural cells as well as fibroblast, epithelial and a variety of tumor cell lines (PMID: 8999038). It has also been shown that OSMR associates with IL31RA to form the heterodimeric IL31 receptor (PMID: 15184896).
