Validation Data Gallery
Filter:
Tested Applications
| Positive WB detected in | A549 cells, mouse liver tissue, mouse ovary tissue, rat ovary tissue |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:500-1:3000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Published Applications
| KD/KO | See 1 publications below |
| WB | See 7 publications below |
| IHC | See 1 publications below |
| IP | See 1 publications below |
Product Information
15248-1-AP targets OSGIN1 in WB, IHC, IP, ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | OSGIN1 fusion protein Ag4295 相同性解析による交差性が予測される生物種 |
| Full Name | oxidative stress induced growth inhibitor 1 |
| Calculated molecular weight | 61 kDa |
| Observed molecular weight | 38 kDa, 52 kDa, 61 kDa |
| GenBank accession number | BC032476 |
| Gene Symbol | OSGIN1 |
| Gene ID (NCBI) | 29948 |
| RRID | AB_2156401 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q9UJX0 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
OSGIN1, also named as BDGI and OKL38, belongs to the OKL38 family. OSGIN1 is a gene linked to oxidative stress and cell death in other tissues, was markedly upregulated in smokers compared to nonsmokers (PMID: 28548877). OSGIN1 has 3 isoforms with the molecular mass of 38, 52 and 61 kDa (PMID: 28181536).
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for OSGIN1 antibody 15248-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
| Species | Application | Title |
|---|---|---|
J Hazard Mater METTL3 regulates PM2.5-induced cell injury by targeting OSGIN1 in human airway epithelial cells. | ||
Cell Mol Life Sci OSGIN1 is a novel TUBB3 regulator that promotes tumor progression and gefitinib resistance in non-small cell lung cancer | ||
Toxicol Lett LncRNA UCA1 attenuates autophagy-dependent cell death through blocking autophagic flux under arsenic stress.
| ||
J Pharmacol Exp Ther Mechanistic Analysis of an Extracellular Signal-Regulated Kinase 2-Interacting Compound that Inhibits Mutant BRAF-Expressing Melanoma Cells by Inducing Oxidative Stress. | ||
Toxicol Lett OSGIN1 regulates PM2.5-induced fibrosis via mediating autophagy in an in vitro model of COPD | ||
Int J Mol Sci Methylmercury Induces Apoptosis in Mouse C17.2 Neural Stem Cells through the Induction of OSGIN1 Expression by NRF2 |