OGDHL Recombinant antibody
OGDHL Recombinant Antibody for IF, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
Human
Applications
IF, ELISA
Conjugate
Unconjugated
CloneNo.
230228B2
Cat no : 82981-1-RR
Synonyms
Validation Data Gallery
Tested Applications
| Positive IF detected in | U2OS cells |
Recommended dilution
| Application | Dilution |
|---|---|
| Immunofluorescence (IF) | IF : 1:150-1:600 |
| Sample-dependent, check data in validation data gallery | |
Product Information
82981-1-RR targets OGDHL in IF, ELISA applications and shows reactivity with Human samples.
| Tested Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | OGDHL fusion protein Ag10794 相同性解析による交差性が予測される生物種 |
| Full Name | oxoglutarate dehydrogenase-like |
| Calculated molecular weight | 1010 aa, 115 kDa |
| GenBank accession number | BC026320 |
| Gene symbol | OGDHL |
| Gene ID (NCBI) | 55753 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
OGDHL(oxoglutarate dehydrogenase-like) is also named as KGDE1KL, FLJ10851, KIAA1290 and belongs to the alpha-ketoglutarate dehydrogenase family. OGDHL is one of the rate-limiting component of the multienzyme OGDH complex (OGDHC) whose malfunction is associated with neuro-degeneration and it is localized only in the mitochondrial fraction and not in the cytosolic or nuclear fractions(PMID:23152800). OGDHL negatively regulates cell proliferation by inducing apoptosis in cervical cancer cells. It may thus participate in brain-specific control of 2-oxoglutarate distribution between energy production and synthesis of the neurotransmitter glutamate(PMID:18783430). It has 3 isoforms(114 kDa, 108 kDa, 91 kDa) produced by alternative splicing.
Protocols
| Product Specific Protocols | |
|---|---|
| IF protocol for OGDHL antibody 82981-1-RR | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
