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Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

OATP1B3 Polyclonal antibody

OATP1B3 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 22815-1-AP

Synonyms

LST 2, LST 3TM13, LST2, LST3, OATP 8, OATP1B3, OATP8, Organic anion transporter 8, SLC21A8, SLCO1B3

Validation Data Gallery

Applications:
  • WB analysis using 22815-1-AP

    WB analysis using 22815-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 22815-1-AP (OATP1B3 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

Tested Applications

Positive WB detected inHeLa cells, L02 cells, human placenta tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
Sample-dependent, check data in validation data gallery

Product Information

22815-1-AP targets OATP1B3 in WB, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen OATP1B3 fusion protein Ag18940 相同性解析による交差性が予測される生物種
Full Name solute carrier organic anion transporter family, member 1B3
Calculated molecular weight 702 aa, 77 kDa
Observed molecular weight 70-75 kDa
GenBank accession numberBC105597
Gene symbol SLCO1B3
Gene ID (NCBI) 28234
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

SLCO1B3, also known as OATP8 or OATP1B3, is a member of Organic Anion Transporting Polypeptides (OATPs) which are sodium-independent organic anion transporters mediating the uptake of a wide range of structurally diverse endogenous and exogenous compounds including bile acids, hormone conjugates, peptides, toxins, as well as a multitude of therapeutic drugs. SLCO1B3 is specifically expressed in liver under normal condition, while its expression has also been observed in cancer tissues like colon, prostate and pancreas. SLCO1B3 is a glycosylated protein and can be detected in the non-glycosylated form at 70-75 kDa(PMID: 21278621).

Protocols

Product Specific Protocols
WB protocol for OATP1B3 antibody 22815-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols