Validation Data Gallery
Product Information
69007-1-PBS targets NeutraKine® IFN-gamma in Neutralization, ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | human Humankine IFN-gamma protein HZ-1301 相同性解析による交差性が予測される生物種 |
Full Name | IFN gamma |
Gene Symbol | IFNG |
Gene ID (NCBI) | 3458 |
ENSEMBL Gene ID | ENSG00000111537 |
RRID | AB_2882925 |
Conjugate | Unconjugated |
Form | |
Purification Method | Protein G purification |
UNIPROT ID | P01579 |
Storage Buffer | PBS only{{ptg:BufferTemp}}7.3 |
Storage Conditions | Store at -80°C. |
Background Information
Interferon gamma (IFNG) is a soluble cytokine that is the only member of the type II class of interferons. It is secreted by Th1 cells, cytotoxic T cells and NK cells. The cytokine is associated with antiviral, immunoregulatory and anti-tumor properties and is a potent activator of macrophages. It plays crucial roles in pathogen clearance. Aberrant IFNG expression is associated with a number of autoinflammatory and autoimmune diseases. It has been identified in many studies as a biomarker for pleural tuberculosis (TB). Mutations in this gene are associated with aplastic anemia.
This antibody can be used to neutralize the bioactivity of Interferon gamma.