Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
34385-1-PBS targets NUDT7 in WB, IP, Indirect ELISA applications and shows reactivity with human, mouse samples.
| Tested Reactivity | human, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag41199 Product name: Recombinant human NUDT7 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 37-172 aa of NM_001105663 Sequence: YNKYSVLLPLVAKEGKLHLLFTVRSEKLRRAPGEVCFPGGKRDPTDMDDAATALREAQEEVGLRPHQVEVVCCLVPCLIDTDTLITPFVGLIDHNFQAQPNPAEVKDVFLVPLAYFLHPQVHDQHYVTRLGHRFIN 相同性解析による交差性が予測される生物種 |
| Full Name | nudix (nucleoside diphosphate linked moiety X)-type motif 7 |
| Calculated molecular weight | 238aa, 27 kDa |
| Observed molecular weight | 30 kDa |
| GenBank accession number | NM_001105663 |
| Gene Symbol | NUDT7 |
| Gene ID (NCBI) | 283927 |
| RRID | AB_3743196 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Antigen affinity Purification |
| UNIPROT ID | P0C024 |
| Storage Buffer | PBS only{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
Peroxisomal coenzyme A diphosphatase NUDT7, a peroxisomal Nudix hydrolase, mainly localizes to the peroxisomal matrix and catalyzes hydrolysis of CoA/acyl-CoAs, regulating lipid metabolism and CoA homeostasis (PMID: 11415433; 25110012). Its dysregulation links to diabetes, Kras-driven colorectal cancer, neurodegeneration with brain iron accumulation, and osteoarthritis (PMID: 32131398; 24847269; 30143643).