Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Published Applications
| WB | See 1 publications below |
| IHC | See 1 publications below |
Product Information
11197-1-AP targets NOTCH2 in WB, IHC, ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Cited Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | NOTCH2 fusion protein Ag1679 相同性解析による交差性が予測される生物種 |
| Full Name | Notch homolog 2 (Drosophila) N-terminal like |
| Calculated molecular weight | 265 kDa |
| GenBank accession number | BC019835 |
| Gene Symbol | NOTCH2NL |
| Gene ID (NCBI) | 388677 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P0DPK4 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
Notch2 is another homologue gene of Norch in Drosophila. It is a 300kd transmembrane protein, with one 110kd processed fragment, on western blotting. Notch2, like other Norch genes, functions in development of various tissues. This antibody can recognize NOTCH2 and NOTCH2NL.
Publications
| Species | Application | Title |
|---|---|---|
Cancer Lett LRP1 induces anti-PD-1 resistance by modulating the DLL4-NOTCH2-CCL2 axis and redirecting M2-like macrophage polarisation in bladder cancer |