NOTCH2/NOTCH2NL Polyclonal antibody

NOTCH2 Polyclonal Antibody for ELISA
Cat No. 11197-1-AP

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, ELISA

N2N, NOTCH2, NOTCH2NL

Formulation:  PBS, Azide, Glycerol
PBS, Azide, Glycerol
Conjugate:  Unconjugated
Size/Concentration: 

-/ -


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保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換/補填対応を承ります。詳細はこちらをご覧ください。


Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

11197-1-AP targets NOTCH2 in WB, IHC, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Cited Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen

CatNo: Ag1679

Product name: Recombinant human NOTCH2 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-254 aa of BC019835

Sequence: PAHALQCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGICLNLPGSYQCQCLQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPETVRRGTELWERDREVWNGKEHDEN

相同性解析による交差性が予測される生物種
Full Name Notch homolog 2 (Drosophila) N-terminal like
Calculated molecular weight 265 kDa
GenBank accession numberBC019835
Gene Symbol NOTCH2NL
Gene ID (NCBI) 388677
Conjugate Unconjugated
Form
FormLiquid
Purification MethodAntigen affinity purification
UNIPROT IDP0DPK4
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol{{ptg:BufferTemp}}7.3
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

Notch2 is another homologue gene of Norch in Drosophila. It is a 300kd transmembrane protein, with one 110kd processed fragment, on western blotting. Notch2, like other Norch genes, functions in development of various tissues. This antibody can recognize NOTCH2 and NOTCH2NL.

Publications

SpeciesApplicationTitle
humanWB,IHC

Cancer Lett

LRP1 induces anti-PD-1 resistance by modulating the DLL4-NOTCH2-CCL2 axis and redirecting M2-like macrophage polarisation in bladder cancer

Authors - Hansen Lin
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