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Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
84355-1-PBS targets NKX6-1 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | Peptide 相同性解析による交差性が予測される生物種 |
| Full Name | NK6 homeobox 1 |
| Calculated molecular weight | 38 kDa |
| Observed molecular weight | 45-52 kDa |
| GenBank accession number | NM_006168 |
| Gene Symbol | NKX6-1 |
| Gene ID (NCBI) | 4825 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purfication |
| UNIPROT ID | P78426 |
| Storage Buffer | PBS only , pH 7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
NK6 homeobox 1 (NKX6-1) is a potent bifunctional transcription regulator that binds to AT-rich DNA sequences within the promoter region of target genes. NKX6-1 belongs to the class II proteins of neuronal progenitor factors, and the function of it is to enhance proliferation, glucose-stimulated insulin secretion, and survival in mature pancreatic beta-cells, and it is also essential in regional patterning and neuronal fate determination in central nervous system.