MultiProTM-5CFLX Anti-Human Cyclin D3 (1F2C6)
Cyclin D3 Monoclonal Antibody for
Host / Isotype
Mouse / IgG1
Reactivity
Human
Applications
Conjugate
5CFLX Fluorescent Dye
CloneNo.
1F2C6
Cat no : G66357-1-5C
Synonyms
Validation Data Gallery
Tested Applications
Positive Single Cell (Intra) detected in | 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product |
Recommended dilution
Application | Dilution |
---|---|
SINGLE CELL (INTRA) | SINGLE CELL (INTRA) : <0.5ug/test |
Sample-dependent, check data in validation data gallery |
Product Information
G66357-1-5C targets Cyclin D3 in applications and shows reactivity with Human samples.
Tested Reactivity | Human |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | Cyclin D3 fusion protein Ag22825 相同性解析による交差性が予測される生物種 |
Full Name | cyclin D3 |
Calculated molecular weight | 33 kDa |
GenBank accession number | BC011616 |
Gene symbol | CCND3 |
Gene ID (NCBI) | 896 |
Conjugate | 5CFLX Fluorescent Dye |
Form | Liquid |
Purification Method | |
Storage Buffer | PBS with 1mM EDTA and 0.09% sodium azide |
Storage Conditions | 2-8°C |
Background Information
Cyclin D3 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activitiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation.