MultiProTM-5CFLX Anti-Human CD31 (3F8E2)
CD31 Monoclonal Antibody for
Host / Isotype
Mouse / IgG1
Reactivity
Human
Applications
Conjugate
5CFLX Fluorescent Dye
CloneNo.
3F8E2
Cat no : G66065-2-5C
Synonyms
Validation Data Gallery
Tested Applications
Positive Single Cell (Intra) detected in | 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product |
Positive Single Cell detected in | 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product |
Recommended dilution
Application | Dilution |
---|---|
SINGLE CELL (INTRA) | SINGLE CELL (INTRA) : <0.5ug/test |
SINGLE CELL | SINGLE CELL : <0.5ug/test |
Sample-dependent, check data in validation data gallery |
Product Information
G66065-2-5C targets CD31 in applications and shows reactivity with Human samples.
Tested Reactivity | Human |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | CD31 fusion protein Ag19730 相同性解析による交差性が予測される生物種 |
Full Name | platelet/endothelial cell adhesion molecule |
Calculated molecular weight | 83 kDa |
GenBank accession number | BC022512 |
Gene symbol | PECAM1 |
Gene ID (NCBI) | 5175 |
Conjugate | 5CFLX Fluorescent Dye |
Form | Liquid |
Purification Method | |
Storage Buffer | PBS with 1mM EDTA and 0.09% sodium azide |
Storage Conditions | 2-8°C |
Background Information
Platelet endothelial cell adhesion molecule-1 (PECAM-1, CD31) is a member of the immunoglobulin gene superfamily of cell adhesion molecules. CD31 is a transmembrane glycoprotein that is highly expressed on the surface of the endothelium, making up a large portion of its intracellular junctions. PECAM-1 is also present on the surface of hematopoietic cells and immune cells including platelets, monocytes, neutrophils, natural killer cells, megakaryocytes and some types of T-cell (PMID: 9011572). As well as its role in cell-cell adhesion, PECAM-1 functions as a signaling receptor, and is involved in important physiological events such as nitric oxide production, regulation of T-cell immunity and tolerance, leukocyte transendothelial migration and inflammation and angiogenesis (PMID: 21183735; 20978210; 17872453; 20634489).