MultiProTM-5CFLX Anti-Human CD19 (HIB19)
CD19 Monoclonal Antibody for
Host / Isotype
Mouse / IgG1, kappa
Reactivity
Human
Applications
Conjugate
5CFLX Fluorescent Dye
CloneNo.
HIB19
Cat no : G65110-1-5C
Synonyms
Validation Data Gallery
Tested Applications
Positive Single Cell (Intra) detected in | 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product |
Positive Single Cell detected in | 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product |
Recommended dilution
Application | Dilution |
---|---|
SINGLE CELL (INTRA) | SINGLE CELL (INTRA) : <0.5ug/test |
SINGLE CELL | SINGLE CELL : <0.5ug/test |
Sample-dependent, check data in validation data gallery |
Product Information
G65110-1-5C targets CD19 in applications and shows reactivity with Human samples.
Tested Reactivity | Human |
Host / Isotype | Mouse / IgG1, kappa |
Class | Monoclonal |
Type | Antibody |
Immunogen | N/A 相同性解析による交差性が予測される生物種 |
Full Name | CD19 molecule |
Calculated molecular weight | 556 aa, 61 kDa |
GenBank accession number | BC006338 |
Gene symbol | CD19 |
Gene ID (NCBI) | 930 |
Conjugate | 5CFLX Fluorescent Dye |
Form | Liquid |
Purification Method | |
Storage Buffer | PBS with 1mM EDTA and 0.09% sodium azide |
Storage Conditions | 2-8°C |
Background Information
CD19 is a 95 kDa type I transmembrane glycoprotein belonging to the immunoglobulin superfamily (PMID: 2472450). It is expressed by B cells and follicular dendritic cells. CD19 is up-regulated at the step of B-lineage commitment during the differentiation of the hematopoietic stem cell, it remains on during subsequent stages of differentiation until finally down-regulated during terminal differentiation into plasma cells (PMID: 8528044). CD19 is involved in B cell development, activation and differentiation. It is the dominant component for the signaling complex on B cells that includes CD21 (CR2), CD81 (TAPA-1) and CD225 and acts as a critical co-receptor for BCR signal transduction (PMID: 23210908).