MultiProTM-5CFLX Anti-Human AHNAK (Polyclonal)
AHNAK Polyclonal Antibody for
Host / Isotype
Rabbit / IgG
Reactivity
Human
Applications
Conjugate
5CFLX Fluorescent Dye
Cat no : G16637-1-5C
Synonyms
Validation Data Gallery
Tested Applications
| Positive Single Cell (Intra) detected in | 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product |
Recommended dilution
| Application | Dilution |
|---|---|
| SINGLE CELL (INTRA) | SINGLE CELL (INTRA) : <0.5ug/test |
| Sample-dependent, check data in validation data gallery | |
Product Information
G16637-1-5C targets AHNAK in applications and shows reactivity with Human samples.
| Tested Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | AHNAK fusion protein Ag9986 相同性解析による交差性が予測される生物種 |
| Full Name | AHNAK nucleoprotein |
| Calculated molecular weight | 629 kDa |
| GenBank accession number | BC000926 |
| Gene symbol | AHNAK |
| Gene ID (NCBI) | 79026 |
| Conjugate | 5CFLX Fluorescent Dye |
| Form | Liquid |
| Purification Method | |
| Storage Buffer | PBS with 1mM EDTA and 0.09% sodium azide |
| Storage Conditions | 2-8°C |
Background Information
AHNAK, also known as desmoyokin, is described as a giant scaffold protein based on its large size (629 kDa) and ability to interact with different proteins to form multi-protein complexes. The bulk of the protein is assembled in 128-residue repetitive elements known as the central repeated unit (CRU). Its proposed functions are quite diverse, ranging from a role in the formation of the blood brain barrier, in cell architecture and migration, to the regulation of cardiac channels and muscle membrane repair. AHNAK is differentially expressed in some cancer cell lines. The expression of AHNAK is subsequently localized to the plasma membrane of keratinocytes in human epidermis. AHNAK has been reported in many intracellular locations including the nucleus, cytoplasm and plasma membrane.
