Recombinant Mouse TCB1 protein (rFc Tag)
Species
Mouse
Purity
>90 %, SDS-PAGE
Tag
rFc Tag
Activity
not tested
Cat no : Eg2437
Validation Data Gallery
Product Information
| Purity | >90 %, SDS-PAGE |
| Endotoxin | <0.1 EU/μg protein, LAL method |
| Activity |
Not tested |
| Expression | HEK293-derived Mouse TCB1 protein Glu1-Ser140 (Accession# P01852) with a rabbit IgG Fc tag at the C-terminus. |
| GeneID | |
| Accession | P01852 |
| PredictedSize | 42.0 kDa |
| SDS-PAGE | 42-55 kDa, reducing (R) conditions |
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| Reconstitution | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| Storage Conditions |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
Background
TCB1(T-cell receptor beta-1 chain C region) is one of the constant regions of T cell receptor (TR) beta chain and includes V (variable), J (joining), diversity (D), and C (constant) segments. TCB1 is synthesized through DNA-level recombination events during T cell development and is involved in antigen recognition and immune response of T cells.
References:
1. Paul M Maciocia , et al. (2017) Nat Med. 23(12):1416-1423. 2. Fanlin Li , et al. (2022) Nat Commun. 13(1):4334. 3. Marie-Paule Lefranc , et al. (2014) Front Immunol. 5:22.