Recombinant Mouse ST6GAL1 protein (rFc Tag)
Species
Mouse
Purity
>90 %, SDS-PAGE
Tag
rFc Tag
Activity
not tested
Cat no : Eg5251
Validation Data Gallery
Product Information
| Purity | >90 %, SDS-PAGE |
| Endotoxin | <0.1 EU/μg protein, LAL method |
| Activity |
Not tested |
| Expression | HEK293-derived Mouse ST6GAL1 protein Lys27-Cys403 (Accession# Q64685) with a rabbit IgG Fc tag at the C-terminus. |
| GeneID | 20440 |
| Accession | Q64685 |
| PredictedSize | 69.0 kDa |
| SDS-PAGE | 65-83 kDa, reducing (R) conditions |
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| Reconstitution | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| Storage Conditions |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
Background
ST6GAL1 (β-galactoside α-2-6 sialyl transferase1; also known as ST6N or CD75) is a sialyltransferase mediating the glycosylation of proteins and lipids to form functionally important glycoproteins and glycolipids in the Golgi compartment. It is principally expressed in liver, placenta, and skeletal muscle. ST6GAL1 undergoes proteolytic process to generate soluble form from membrane form.
References:
1. Krick, Stefanie et al. Frontiers in immunology vol. 12 (2021): 693149. 2. Gc, Sajina et al. Frontiers in molecular biosciences vol. 9 (2022): 962908. 3. Swindall, Amanda F et al. Cancer research vol. 73,7 (2013): 2368-78.