Recombinant Mouse MST1R protein (rFc Tag) (HPLC verified)
Species
Mouse
Purity
>90 %, SDS-PAGE
>90 %, SEC-HPLC
Tag
rFc Tag
Activity
not tested
Cat no : Eg2647
Validation Data Gallery
Product Information
| Purity | >90 %, SDS-PAGE >90 %, SEC-HPLC |
| Endotoxin | <0.1 EU/μg protein, LAL method |
| Activity |
Not tested |
| Expression | CHO-derived Mouse MST1R protein Thr25-Arg960 (Accession# Q62190-1) with a rabbit IgG Fc tag at the C-terminus. |
| GeneID | 19882 |
| Accession | Q62190-1 |
| PredictedSize | 127.2 kDa |
| SDS-PAGE | 28-32 kDa, 90-120 kDa and 200-220 kDa, reducing (R) conditions |
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| Reconstitution | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| Storage Conditions |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
Background
Mst1r (macrophage-stimulating 1 receptor), encodes a cell surface receptor for macrophage-stimulating 1 (MST1, also known as MSP) with tyrosine kinase activity. Mst1r is critical for innate immunity and plays an important role for host defense against viral infection. The upregulation of MST1R tyrosine kinase expression is a molecular event of particular interest in many epithelial neoplasms, as it can mediate oncogenic phenotypes and addiction to KRAS signaling.
References:
1. Dai W, et al. (2016). Proc Natl Acad Sci U S A. Mar 22;113(12):3317-22. 2. Babicky, M. L., et al. (2019). Oncogene. Jul;38(28):5599-5611. 3. Wang W, et al. (2024). Cell Biosci. Aug 29;14(1):109.