Speedy™ Mouse IL-13RA2 One-Step ELISA Kit
Sensitivity
0.04 ng/mL
Range
0.156-10 ng/mL
Reactivity
Mouse
Cat no : SE60011
Synonyms
CD213a2, IL-13 receptor subunit alpha-2, IL-13R subunit alpha-2, Il13ra2, IL-13R-alpha-2
Validation Data Gallery
Product Information
| Product name | Speedy™ Mouse IL-13RA2 One-Step ELISA Kit |
| Tests | 1 X 96 well plate |
| Sample type | Serum, Plasma, Tissue homogenates |
| Assay type | Sandwich |
| Sensitivity | 0.04 ng/mL |
| Range | 0.156-10 ng/mL |
| Reactivity | Mouse |
| Tested applications | Sandwich ELISA |
| Gene ID (NCBI) | 16165 |
Recovery
| Sample Type | Average | Range |
|---|---|---|
| Mouse serum | 96% | 94%-98% |
| Tissue homogenates | 92% | 88%-97% |
IntraAssay
| Sample | n | mean ( ng/mL) | SD | CV% |
|---|---|---|---|---|
| 1 | 8 | 5.20 | 0.17 | 3.27 |
| 2 | 8 | 1.26 | 0.03 | 2.38 |
| 3 | 8 | 0.64 | 0.01 | 1.56 |
InterAssay
| Sample | n | mean ( ng/mL) | SD | CV% |
|---|---|---|---|---|
| 1 | 16 | 5.13 | 0.17 | 3.31 |
| 2 | 16 | 1.26 | 0.03 | 2.38 |
| 3 | 16 | 0.64 | 0.01 | 1.56 |
Background Information
IL-13RA2, also known as IL-13R and CD213a2, belongs to the type I cytokine receptor family. It binds as a monomer with high affinity to interleukin-13 (IL-13), but not to interleukin-4 (IL-4). IL-13RA2 lacks the cytoplasmic domain for signaling, indicating that it acts as a decoy receptor. IL13RA2 polymorphisms have been associated with systemic sclerosis. Overexpression of IL-13RA2 has been reported in several types of cancer, including melanoma, lung cancer, and brain tumor, which makes it a potential immunotherapeutic target.
Properties
| Storage Instructions | All the reagents are stored at 2-8℃ for 6 months or -20℃ for 12 months. Refer to the protocol for further storage instructions. |
| Synonyms | CD213a2, IL-13 receptor subunit alpha-2, IL-13R subunit alpha-2, Il13ra2, IL-13R-alpha-2 |