Recombinant Mouse Galanin protein (rFc Tag)
Species
Mouse
Purity
>90 %, SDS-PAGE
Tag
rFc Tag
Activity
not tested
Cat no : Eg2758
Validation Data Gallery
Product Information
| Purity | >90 %, SDS-PAGE |
| Endotoxin | <0.1 EU/μg protein, LAL method |
| Activity |
Not tested |
| Expression | HEK293-derived Mouse Galanin protein Ala20-Ser124 (Accession# P47212) with a rabbit IgG Fc tag at the C-terminus. |
| GeneID | 14419 |
| Accession | P47212 |
| PredictedSize | 37.5 kDa |
| SDS-PAGE | 36-42 kDa, reducing (R) conditions |
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| Reconstitution | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| Storage Conditions |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
Background
Galanin is a neuroendocrine peptide that is widely expressed in the central and peripheral nervous systems and also the gastrointestinal tract, pancreas, adrenal gland and urogenital tract. The encoded protein is a precursor that is proteolytically processed to generate two mature peptides: galanin and galanin message-associated peptide (GMAP). Galanin has diverse physiological functions including nociception, feeding and energy homeostasis, osmotic regulation, and water balance. GMAP has been demonstrated to possess antifungal activity and is hypothesized to be part of the innate immune system
References:
1. W E Schmidt, et al. (1991). Proc Natl Acad Sci U S A. 88(24):11435-9. 2. Sipin Zhu, et al. (2022). Front Endocrinol (Lausanne). 13:1019943. 3. J Šípková, et al. (2017). Physiol Res. 66(5):729-740.