Recombinant Mouse Ctf1 protein (rFc Tag)
Species
Mouse
Purity
>90 %, SDS-PAGE
Tag
rFc Tag
Activity
not tested
Cat no : Eg2867
Validation Data Gallery
Product Information
| Purity | >90 %, SDS-PAGE |
| Endotoxin | <1.0 EU/μg protein, LAL method |
| Activity |
Not tested |
| Expression | HEK293-derived Mouse Ctf1 protein Ser2-Ala203 (Accession# Q60753) with a rabbit IgG Fc tag at the C-terminus. |
| GeneID | 13019 |
| Accession | Q60753 |
| PredictedSize | 47.0 kDa |
| SDS-PAGE | |
| Formulation | Lyophilized from sterile PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| Reconstitution | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| Storage Conditions |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
Background
CTF1 (Cardiotrophin-1) is a member of the interleukin-6 (IL-6) family of cytokines. It is a secreted protein that induces cardiac myocyte hypertrophy in vitro and has been shown to bind and activate the IL-6ST/gp130 receptor. CTF1 plays a crucial role in various physiological and pathological processes, including cardiac function, metabolism, and cancer progression.
References:
1.Bustos, Matilde et al. Oncoimmunology vol. 1,9 (2012): 1527-1536. 2.Ping, Ying et al. Journal of clinical laboratory analysis vol. 35,4 (2021): e23570. 3.Tsuruda, Toshihiro et al. Circulation research vol. 90,2 (2002): 128-34. 4.Moreno-Aliaga, María J et al. Cell metabolism vol. 14,2 (2011): 242-53. 5.Akkoc, Yunus et al. Autophagy vol. 19,1 (2023): 306-323.