Recombinant Mouse CD98/SLC3A2 protein (rFc Tag)(HPLC verified)
Species
Mouse
Purity
>90 %, SDS-PAGE
>90 %, SEC-HPLC
Tag
rFc Tag
Activity
not tested
Cat no : Eg1547
Validation Data Gallery
Product Information
| Purity | >90 %, SDS-PAGE >90 %, SEC-HPLC |
| Endotoxin | <0.1 EU/μg protein, LAL method |
| Activity |
Not tested |
| Expression | HEK293-derived Mouse CD98 protein Ala100-Ala526 (Accession# P10852-1) with a rabbit IgG Fc tag at the N-terminus. |
| GeneID | 17254 |
| Accession | P10852-1 |
| PredictedSize | 74.8 kDa |
| SDS-PAGE | 75-100 kDa, reducing (R) conditions |
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| Reconstitution | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| Storage Conditions |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
Background
CD98 (SLC3A2) is a solute carrier family protein that is a component of the amino acid transporter and pairs with another solute carrier family protein, such as L-type amino acid transporter 1 (LAT1/SLC7A5) or cystine/glutamate transporter (xCT/SLC7A11). CD98 is known to play a role in delivering amino acids into and out of cells as an amino acid transporter. CD98 is highly upregulated in various cancer cells and promotes cancer cell survival, migration, invasion, angiogenesis and drug resistance.
References:
1. Lee Y. et al. (2019). Nat Struct Mol Biol. 26:510–517. 2. Xia P. et al. (2023). Front Oncol. 13:1251100. 3. Lim K. et al. (2024). Cancer Immunol Immunother. 73(11):231.