Recombinant Mouse CD84/SLAMF5 protein (His Tag)
Species
Mouse
Purity
>90 %, SDS-PAGE
Tag
His Tag
Activity
not tested
Cat no : Eg1313
Validation Data Gallery
Product Information
| Purity | >90 %, SDS-PAGE |
| Endotoxin | <1.0 EU/μg protein, LAL method |
| Activity |
Not tested |
| Expression | HEK293-derived Mouse CD84/SLAMF5 protein Lys22-Val221 (Accession# Q18PI6-1) with a His tag at the C-terminus. |
| GeneID | 12523 |
| Accession | Q18PI6-1 |
| PredictedSize | 23.6 kDa |
| SDS-PAGE | |
| Formulation | Lyophilized from sterile PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| Reconstitution | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| Storage Conditions |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
Background
CD84, also known as SLAMF5, is a member of the CD2 subfamily of the immunoglobulin receptor superfamily. CD84 is a single-chain type-I glycoprotein composed of two extracellular Ig-like domains, a hydrophobic transmembrane region, and a cytoplasmic domain. It is broadly expressed on almost all leukocyte subsets. CD84 functions as a homophilic adhesion molecule, whose signaling can activate or inhibit leukocyte function depending on the cell type and its stage of activation or differentiation.
References:
1. de la Fuente, M A et al. Blood vol. 90,6 (1997): 2398-405. 2. Cuenca, Marta et al. Clinical immunology (Orlando, Fla.) vol. 204 (2019): 43-49. 3. Martin, M et al. Journal of immunology (Baltimore, Md. : 1950) vol. 167,7 (2001): 3668-76.