• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0
×

Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

Use Able AI chat for product recommendations

Validation Data Gallery

Filter:
  • Western Blot (WB) analysis of various lysates using MTMR4 Polyclonal antibody (13488-1-AP)

    WB analysis using 13488-1-AP (same clone as 13488-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 13488-1-AP (MTMR4 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13488-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of MCF-7 cells using MTMR4 Polyclonal antibody (13488-1-AP)

    WB analysis of MCF-7 using 13488-1-AP (same clone as 13488-1-PBS)

    WB result of MTMR4 antibody (13488-1-AP; 1:600; incubated at room temperature for 1.5 hours) with sh-Control and sh-MTMR4 transfected MCF-7 cells. This data was developed using the same antibody clone with 13488-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using MTMR4 Polyclonal antibody (13488-1-AP)

    WB analysis using 13488-1-AP (same clone as 13488-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 13488-1-AP (MTMR4 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13488-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of Hepatocellular carcinoma tissue using MTMR4 Polyclonal antibody (13488-1-AP)

    IHC staining of Hepatocellular carcinoma using 13488-1-AP (same clone as 13488-1-PBS)

    Immunohistochemical analysis of paraffin-embedded hepatocellular carcinoma tissue slide using 13488-1-AP (MTMR4 antibody) at dilution of 1:1000 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13488-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of Hepatocellular carcinoma tissue using MTMR4 Polyclonal antibody (13488-1-AP)

    IHC staining of Hepatocellular carcinoma using 13488-1-AP (same clone as 13488-1-PBS)

    Immunohistochemical analysis of paraffin-embedded hepatocellular carcinoma tissue slide using 13488-1-AP (MTMR4 antibody) at dilution of 1:1000 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13488-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of rat testis tissue using MTMR4 Polyclonal antibody (13488-1-AP)

    IHC staining of rat testis using 13488-1-AP (same clone as 13488-1-PBS)

    Immunohistochemical analysis of paraffin-embedded rat testis tissue slide using 13488-1-AP (MTMR4 antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13488-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of rat testis tissue using MTMR4 Polyclonal antibody (13488-1-AP)

    IHC staining of rat testis using 13488-1-AP (same clone as 13488-1-PBS)

    Immunohistochemical analysis of paraffin-embedded rat testis tissue slide using 13488-1-AP (MTMR4 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13488-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of HepG2 cells using MTMR4 Polyclonal antibody (13488-1-AP)

    IF Staining of HepG2 using 13488-1-AP (same clone as 13488-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using MTMR4 antibody (13488-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 13488-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO Validated

MTMR4 Polyclonal antibody, PBS Only

MTMR4 Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA
Cat No. 13488-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, IF/ICC, Indirect ELISA

Synonyms

EC:3.1.3.48, FYVE domain-containing dual specificity protein phosphatase 2, FYVE DSP2, FYVE-DSP2, KIAA0647

Formulation:  PBS Only
PBS, Azide, Glycerol
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

ご購入について

国内販売は「コスモ・バイオ株式会社」を通じて行っております。お見積り・ご注文はお近くの販売代理店へご連絡ください。

国内在庫・納期について

約2万点のプロテインテック製品をコスモバイオ社物流センター（国内）に在庫しています。国内在庫の有無はコスモバイオ社ホームページの「品番検索」でカタログ番号を検索して確認できます。

保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換／補填対応を承ります。詳細はこちらをご覧ください。

Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

13488-1-PBS targets MTMR4 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen

CatNo: Ag4310

Product name: Recombinant human MTMR4 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 845-1195 aa of BC035609

Sequence: SHQEQLSSVPDLTHGEEDIGKRGNNRNGQLLENPRFGKMPLELVRKPISQSQISEFSFLGSNWDSFQGMVTSFPSGEATPRRLLSYGCCSKRPNSKQMRATGPCFGGQWAQREGVKSPVCSSHSNGHCTGPGGKNQMWLSSHPKQVSSTKPVPLNCPSPVPPLYLDDDGLPFPTDVIQHRLRQIEAGYKQEVEQLRRQVRELQMRLDIRHCCAPPAEPPMDYEDDFTCLKESDGSDTEDFGSDHSEDCLSEASWEPVDKKETEVTRWVPDHMASHCYNCDCEFWLAKRRHHCRNCGNVFCAGCCHLKLPIPDQQLYDPVLVCNSCYEHIQVSRARELMSQQLKKPIATASS

相同性解析による交差性が予測される生物種
Full Name myotubularin related protein 4
Calculated molecular weight 1195 aa, 133 kDa
Observed molecular weight 133-150 kDa
GenBank accession numberBC035609
Gene Symbol MTMR4
Gene ID (NCBI) 9110
RRIDAB_2251008
Conjugate Unconjugated
Form
FormLiquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9NYA4
Storage Buffer PBS only{{ptg:BufferTemp}}7.3
Storage ConditionsStore at -80°C.

Background Information

Myotubularin-related protein-4 (MTMR4), also named FYVE-DSP2, is a member of the myotubularin family of phosphoinositide phosphatases that selectively degrade the 3-position phosphate from the inositol ring of PtdIns(3)P and phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) (PMID: 31543504). MTMR4 knockdown markedly suppressed the motility, fusion, and fission of PI(3)P- enriched structures, resulting in decreases in late endosomes, autophagosomes, and lysosomes, and enlargement of PI(3)P- enriched early and late endosomes(PMID: 29962048).

||
New chat

Able™

正在加载，请稍候...