Validation Data Gallery
Tested Applications
| Positive WB detected in | A549 cells, HEK-293 cells, human placenta tissue, mouse kidney tissue, mouse liver tissue, rat kidney tissue, rat liver tissue |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:1000-1:8000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
29784-1-AP targets MPZL1 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag31532 Product name: Recombinant human MPZL1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 36-162 aa of BC007881 Sequence: SALEVYTPKEIFVANGTQGKLTCKFKSTSTTGGLTSVSWSFQPEGADTTVSFFHYSQGQVYLGNYPPFKDRISWAGDLDKKDASINIENMQFIHNGTYICDVKNPPDIVVQPGHIRLYVVEKENLPV 相同性解析による交差性が予測される生物種 |
| Full Name | myelin protein zero-like 1 |
| Calculated molecular weight | 29 kDa |
| Observed molecular weight | 32 kDa |
| GenBank accession number | BC007881 |
| Gene Symbol | MPZL1 |
| Gene ID (NCBI) | 9019 |
| RRID | AB_3669695 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | O95297 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
Myelin protein zero-like 1 (MPZL1, also known as PZR) is a transmembrane glycoprotein that promotes the migration of hepatocellular carcinoma cells and is involved in extracellular matrix-induced signal transduction (PMID: 16702974; 8912526). Phosphorylated MPZL1 was linked to the regulation of cell adhesion and migration (PMID: 24296779; 18378677; 12410637). The expression levels of MPZL1 were also associated with malignant features of ovarian cancer (PMID: 31233194).
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for MPZL1 antibody 29784-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |