Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
Published Applications
WB | See 1 publications below |
Product Information
55340-1-AP targets MMP10 in WB, ELISA applications and shows reactivity with human, mouse samples.
Tested Reactivity | human, mouse |
Cited Reactivity | human |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | Peptide 相同性解析による交差性が予測される生物種 |
Full Name | matrix metallopeptidase 10 (stromelysin 2) |
Calculated molecular weight | 54 kDa |
Observed molecular weight | 52 kDa |
GenBank accession number | NM_002425 |
Gene Symbol | MMP10 |
Gene ID (NCBI) | 4319 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | P09238 |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
Storage Conditions | Store at -20°C. Aliquoting is unnecessary for -20oC storage. |
Background Information
MMP10, also named as STMY2, Transin-2, MMP-10, SL-2 and Stromelysin-2, belongs to the peptidase M10A family. It can degrade fibronectin, gelatins of type I, III, IV, and V; weakly collagens III, IV, and V. MMP10 activates procollagenase.Western blot against MMP-10 revealed bands at a molecular weight of about 56 and 42 kDa in serum samples,and the bands with molecular weights of about 42 kDa may be the active forms of MMP-10(PMID:20215736). The expression profile of MMP-10 in several human tumors, coupled with broadsubstrate specificity and expression in several stages of the tumorigenic process suggests MMP-10 as a potential tumor marker and a predictor of clinical behavior, and supports MMP-10 inhibition as a valid therapeutic strategy(PMID:15720804).This antibody is specific to MMP10.
Publications
Species | Application | Title |
---|---|---|
Cancer Cell Int A novel disulfide death-related genes prognostic signature identifies the role of IPO4 in glioma progression |