Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
85876-1-PBS targets MGL2 in WB, Indirect ELISA applications and shows reactivity with mouse samples.
| Tested Reactivity | mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen |
CatNo: Eg2727 Product name: Recombinant Mouse MGL2 protein (rFc Tag) Source: mammalian cells-derived, V37 Tag: C-rFc Domain: 72-332 aa of NM_145137.2 Sequence: SQNSQLRRDLGTLRAILDNTTSKIKAEFQSLDSRADNFEKGISSLKVDVEDHRQELQAGRDLSQKVTSLESTLEKREQALKTDLSDLTDHVQQLETDLKALTCQLANLKNNGSEVACCPLHWTEHEGSCYWFSESEKSWPEADKYCRLENSHLVVVNSLEEQNFLQNRLANVLSWMGLTDQNGPWRWVDGTDFDKGFKNWRPLQPDNWHGHMLGGGEDCAHFSYDGRWNDDVCQRHYHWICETELGKASSAHSPQLIASVP 相同性解析による交差性が予測される生物種 |
| Full Name | macrophage galactose N-acetyl-galactosamine specific lectin 2 |
| Calculated molecular weight | 38 kDa |
| Observed molecular weight | 40 kDa |
| GenBank accession number | NM_145137.2 |
| Gene Symbol | Mgl2 |
| Gene ID (NCBI) | 216864 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | Q8JZN1 |
| Storage Buffer | PBS only{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
MGL2 is mainly expressed on immature dendritic cell (DCs) , tolerogenic DCs, type 2 DCs, and alternatively activated macrophages. MGL2 protein has carbohydrate-binding activity, specifically recognizing and binding to terminal GalNAc (n-acetyl 2-amino-2-deoxy-D-galactopyranose) residues, including the TN antigen (Galnac- αthrser) . This specific binding makes it play an important role in the recognition and processing of glycosylated pathogens, apoptotic cell fragments and tumor cells.