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Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using METTL7B Polyclonal antibody (17001-1-AP)

    WB analysis using 17001-1-AP (same clone as 17001-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 17001-1-AP (METTL7B antibody) at dilution of 1:2500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17001-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of mouse liver tissue using METTL7B Polyclonal antibody (17001-1-AP)

    IHC staining of mouse liver using 17001-1-AP (same clone as 17001-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 17001-1-AP (METTL7B antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17001-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of mouse liver tissue using METTL7B Polyclonal antibody (17001-1-AP)

    IHC staining of mouse liver using 17001-1-AP (same clone as 17001-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 17001-1-AP (METTL7B antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17001-1-PBS in a different storage buffer formulation.

METTL7B Polyclonal antibody, PBS Only

METTL7B Polyclonal Antibody for WB, IHC, ELISA
Cat No. 17001-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, ELISA

Synonyms

EC:2.1.1.9, methyltransferase like 7B, Methyltransferase-like protein 7B, Thiol S-methyltransferase METTL7B, Thiol S-methyltransferase TMT1B

Formulation:  PBS Only
PBS, Azide, Glycerol
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

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国内在庫・納期について

約2万点のプロテインテック製品をコスモバイオ社物流センター（国内）に在庫しています。国内在庫の有無はコスモバイオ社ホームページの「品番検索」でカタログ番号を検索して確認できます。

保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換／補填対応を承ります。詳細はこちらをご覧ください。

Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

17001-1-PBS targets METTL7B in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen

CatNo: Ag10694

Product name: Recombinant human METTL7B protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 39-244 aa of BC020509

Sequence: MAVLTPKSNRKMESKKRELFSQIKGLTGASGKVALLELGCGTGANFQFYPPGCRVTCLDPNPHFEKFLTKSMAENRHLQYERFVVAPGEDMRQLADGSMDVVVCTLVLCSVQSPRKVLQEVRRVLRPGGVLFFWEHVAEPYGSWAFMWQQVFEPTWKHIGDGCCLTRETWKDLENAQFSEIQMERQPPPLKWLPVGPHIMGKAVK

相同性解析による交差性が予測される生物種
Full Name methyltransferase like 7B
Calculated molecular weight244aa,28 kDa
Observed molecular weight 28 kDa
GenBank accession numberBC020509
Gene Symbol METTL7B
Gene ID (NCBI) 196410
RRIDAB_2142199
Conjugate Unconjugated
Form
FormLiquid
Purification MethodAntigen affinity purification
UNIPROT IDQ6UX53
Storage Buffer PBS only{{ptg:BufferTemp}}7.3
Storage ConditionsStore at -80°C.

Background Information

METTL7B is a membrane-associated small-molecule methyltransferase that catalyzes S-methylation of alkyl thiols, thereby linking thiol/sulfur metabolism, redox homeostasis, and cellular stress responses. By influencing antioxidant enzyme expression and detoxification pathways, METTL7B plays a pivotal role in tumor growth and drug resistance, particularly in lung adenocarcinoma. Its upregulation in multiple cancers and involvement in redox/thiol metabolism make it an emerging therapeutic target in oncology and possibly in metabolic/oxidative stress-related disease settings. (PMID: 40068772)

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