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Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using LZTS2 Polyclonal antibody (15677-1-AP)

    WB analysis using 15677-1-AP (same clone as 15677-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 15677-1-AP (LZTS2 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 15677-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of HeLa cells using LZTS2 Polyclonal antibody (15677-1-AP)

    WB analysis of HeLa using 15677-1-AP (same clone as 15677-1-PBS)

    WB result of LZTS2 antibody (15677-1-AP; 1:1000; incubated at room temperature for 1.5 hours) with sh-Control and sh-LZTS2 transfected HeLa cells. This data was developed using the same antibody clone with 15677-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human prostate hyperplasia tissue using LZTS2 Polyclonal antibody (15677-1-AP)

    IHC staining of human prostate hyperplasia using 15677-1-AP (same clone as 15677-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human prostate hyperplasia tissue slide using 15677-1-AP (LZTS2 Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 15677-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human prostate hyperplasia tissue using LZTS2 Polyclonal antibody (15677-1-AP)

    IHC staining of human prostate hyperplasia using 15677-1-AP (same clone as 15677-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human prostate hyperplasia tissue slide using 15677-1-AP (LZTS2 Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 15677-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human kidney tissue using LZTS2 Polyclonal antibody (15677-1-AP)

    IHC staining of human kidney using 15677-1-AP (same clone as 15677-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 15677-1-AP (LZTS2 Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 15677-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human kidney tissue using LZTS2 Polyclonal antibody (15677-1-AP)

    IHC staining of human kidney using 15677-1-AP (same clone as 15677-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 15677-1-AP (LZTS2 Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 15677-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO Validated

LZTS2 Polyclonal antibody, PBS Only

LZTS2 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 15677-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, Indirect ELISA

Synonyms

hLZTS2, LAPSER1, LZTS 2

Formulation:  PBS Only
PBS, Azide, Glycerol
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

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Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

15677-1-PBS targets LZTS2 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen

CatNo: Ag8145

Product name: Recombinant human LZTS2 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 319-669 aa of BC006212

Sequence: PSDEALLHCVLEGKLRDREAELQQLRDSLDENEATMCQAYEERQRHWQREREALREDCAAQAQRAQRAQQLLQLQVFQLQQEKRQLQDDFAQLLQEREQLERRCATLEREQRELGPRLEETKWEVCQKSGEISLLKQQLKESQAELVQKGSELVALRVALREARATLRVSEGRARGLQEAARARELELEACSQELQRHRQEAEQLREKAGQLDAEAAGLREPPVPPATADPFLLAESDEAKVQRAAAGVGGSLRAQVERLRVELQRERRRGEEQRDSFEGERLAWQAEKEQVIRYQKQLQHNYIQMYRRNRQLEQELQQLSLELEARELADLGLAEQAPCICLEEITATEI

相同性解析による交差性が予測される生物種
Full Name leucine zipper, putative tumor suppressor 2
Calculated molecular weight 73 kDa
Observed molecular weight 70-80 kDa
GenBank accession numberBC006212
Gene Symbol LZTS2
Gene ID (NCBI) 84445
RRIDAB_2878166
Conjugate Unconjugated
Form
FormLiquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9BRK4
Storage Buffer PBS only{{ptg:BufferTemp}}7.3
Storage ConditionsStore at -80°C.

Background Information

LZTS2, also named as KIAA1813 and LAPSER1, is a novel b-Catenin-interacting protein and it regulates the nuclear export of b-Catenin. LZTS2 is a negative regulator of katanin-mediated microtubule severing and release from the centrosome. It is required for central spindle formation and the completion of cytokinesis.

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