Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
86291-2-PBS targets LONP2 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.
| Tested Reactivity | human, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen |
CatNo: Ag12650 Product name: Recombinant human LONP2 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 503-852 aa of BC093910 Sequence: DRMEIIQVPGYTQEEKIEIAHRHLIPKQLEQHGLTPQQIQIPQVTTLDIITRYTREAGVRSLDRKLGAICRAVAVKVAEGQHKEAKLDRSDVTEREGCREHILEDEKPESISDTTDLALPPEMPILIDFHALKDILGPPMYEMEVSQRLSQPGVAIGLAWTPLGGEIMFVEASRMDGEGQLTLTGQLGDVMKESAHLAISWLRSNAKKYQLTNAFGSFDLLDNTDIHLHFPAGAVTKDGPSAGVTIVTCLASLFSGRLVRSDVAMTGEITLRGLVLPVGGIKDKVLAAHRAGLKQVIIPRRNEKDLEGIPGNVRQDLSFVTASCLDEVLNAAFDGGFTVKTRPGLLNSKL 相同性解析による交差性が予測される生物種 |
| Full Name | lon peptidase 2, peroxisomal |
| Calculated molecular weight | 852 aa, 95 kDa |
| Observed molecular weight | 95 kDa |
| GenBank accession number | BC093910 |
| Gene Symbol | LONP2 |
| Gene ID (NCBI) | 83752 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | Q86WA8 |
| Storage Buffer | PBS only{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
LONP2 (Lon Peptidase 2, Peroxisomal) is an important ATP-dependent protease. It is primarily located in peroxisomes and is responsible for maintaining the proteostasis of this organelle. By degrading misfolded proteins and selectively regulating metabolic enzymes, LONP2 plays a central role in maintaining peroxisomal proteostasis and metabolic balance. Dysfunction of LONP2 is closely related to a variety of human diseases, including peroxisomal disorders, cancer, and neurodegenerative diseases.