Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
85984-1-PBS targets LILRA5/CD85f in WB, Indirect ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | LILRA5/CD85f fusion protein Eg2737 相同性解析による交差性が予測される生物種 |
Full Name | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 |
Calculated molecular weight | 33 kDa |
Observed molecular weight | 35 kDa |
GenBank accession number | NM_021250.4 |
Gene Symbol | LILRA5 |
Gene ID (NCBI) | 353514 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | A6NI73-1 |
Storage Buffer | PBS only{{ptg:BufferTemp}}7.3 |
Storage Conditions | Store at -80°C. |
Background Information
LILRA5, also named as CD85f, ILT11, LILRB7 or LIR9, is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is a group of immune inhibitory and stimulatory receptors (PMID: 15304001). There are two membrane-bound and two soluble forms of LILRA5. The transmembrane LILRA5 contains a short cytoplasmic domain and a charged arginine residue within the transmembrane region (PMID: 19009525). It is mostly expressed in myeloid cells, including monocytes and neutrophils (PMID: 12393390). LILRA5 may play a role in triggering innate immune responses. It does not function in class I MHC antigens recognition (PMID: 16675463).