Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
CL650-12398 targets LBR in applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | LBR fusion protein Ag3088 相同性解析による交差性が予測される生物種 |
| Full Name | lamin B receptor |
| Calculated molecular weight | 615 aa, 71 kDa |
| Observed molecular weight | 58 kDa |
| GenBank accession number | BC020079 |
| Gene Symbol | LBR |
| Gene ID (NCBI) | 3930 |
| RRID | AB_2920383 |
| Conjugate | CoraLite® Plus 647 Fluorescent Dye |
| Excitation/Emission maxima wavelengths | 654 nm / 674 nm |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q14739 |
| Storage Buffer | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3 |
| Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
Lamin-B receptor (LBR) belongs to the ERG4/ERG24 family. LBR is a 58-kDa integral protein of the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the inner nuclear membrane. LBR may mediate the interaction between chromatin and lamin B. Mutations of the LBR gene have been associated with autosomal recessive HEM/Greenberg skeletal dysplasia.
Protocols
| Product Specific Protocols | |
|---|---|
| FC protocol for CL Plus 647 LBR antibody CL650-12398 | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |