[PR]まずは試したいあなたに。トライアルサイズも特別価格 >>『PRIME BUY抗体特割キャンペーン(4/21~)

KLF6 Monoclonal antibody, PBS Only

KLF6 Monoclonal Antibody for WB, ELISA
Cat No. 67297-1-PBS
Clone No.2F8B3

Host / Isotype

Mouse / IgG1

Reactivity

human, mouse

Applications

WB, ELISA

GC-rich sites-binding factor GBF, CPBP, Core promoter element-binding protein, COPEB, B-cell-derived protein 1

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -


ご購入について

国内販売は「コスモ・バイオ株式会社」を通じて行っております。お見積り・ご注文はお近くの販売代理店へご連絡ください。


国内在庫・納期について

約2万点のプロテインテック製品をコスモバイオ社物流センター(国内)に在庫しています。国内在庫の有無はコスモバイオ社ホームページの「品番検索」でカタログ番号を検索して確認できます。


保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換/補填対応を承ります。詳細はこちらをご覧ください。


Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

67297-1-PBS targets KLF6 in WB, ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen KLF6 fusion protein Ag6859 相同性解析による交差性が予測される生物種
Full Name Kruppel-like factor 6
Calculated molecular weight 32 kDa
Observed molecular weight 32-42 kDa
GenBank accession numberBC000311
Gene Symbol KLF6
Gene ID (NCBI) 1316
RRIDAB_2882561
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ99612
Storage Buffer PBS only , pH 7.3
Storage ConditionsStore at -80°C.

Background Information

KLF6(krupple-like factor 6) is a zinc finger transcription factor and tumor suppressor with biological activities and transcriptional targets in growing range. It is highly expressed in placenta followed by spleen, thymus, prostate, testis, small intestine and colon. One key target gene of KLF6 in endoglin, which is a homodimeric cell membrane glycoprotein and TGF-β auxiliary receptor, owns a pro-angiogenic role in endothelial cells and is also involved in malignant progression. Also KLF6 induces apoptosis in prostate cancer cells through upregulation of ATF3. KLF6 was normal detected as a 46kDa protein, which is larger than translation product(32kDa), because of post-translational modification including both phosphorylation and glycosylation. This antibody raise against the full length of KLF6 gene of human origin, and can recognize both of KLF6, included KLF6(~32kDa), p-KLF6(~35-46kDa). Otherwise, there may be a non-specific band(50kDa) showed in detection

Loading...