Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
30692-1-PBS targets IQGAP2 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.
| Tested Reactivity | human, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag33518 Product name: Recombinant human IQGAP2 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 519-727 aa of NM_006633 Sequence: DEIQQAVDDANVDKDRAKQWVTLVVDVNQCLEGKKSSDILSVLKSSTSNANDIIPECADKYYDALVKAKELKSERVSSDGSWLKLNLHKKYDYYYNTDSKESSWVTPESCLYKESWLTGKEIEDIIEEVTVGYIRENIWSASEELLLRFQATSSGPILREEFEARKSFLHEQEENVVKIQAFWKGYKQRKEYMHRRQTFIDNTDSIVKI 相同性解析による交差性が予測される生物種 |
| Full Name | IQ motif containing GTPase activating protein 2 |
| Calculated molecular weight | 181 kDa |
| Observed molecular weight | 181 kDa |
| GenBank accession number | NM_006633 |
| Gene Symbol | IQGAP2 |
| Gene ID (NCBI) | 10788 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q13576 |
| Storage Buffer | PBS only{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
IQGAP2, a member of the IQGAP family, functions as a tumor suppressor in most of the cancers. IQGAP2 contains three IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. IQGAP2 interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. It also acts as a tumor suppressor and has been found to play a role in regulating innate antiviral responses.