Validation Data Gallery
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Tested Applications
| Positive WB detected in | mouse kidney tissue, human brain tissue |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:500-1:2000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
55112-1-AP targets INSRR in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
Peptide 相同性解析による交差性が予測される生物種 |
| Full Name | IR related receptor |
| Calculated molecular weight | 144 kDa |
| Observed molecular weight | 150-155 kDa |
| GenBank accession number | NM_014215 |
| Gene Symbol | INSRR |
| Gene ID (NCBI) | 3645 |
| RRID | AB_10859077 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P14616 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -20°C. Aliquoting is unnecessary for -20oC storage. |
Background Information
INSRR, also named as IRR, belongs to the protein kinase superfamily, Tyr protein kinase family and INS receptor subfamily. It probably binds an INS related protein and has a tyrosine-protein kinase activity. It phosphorylates the INS receptor substrates IRS-1 and IRS-2. INSRR is a heterotetrameric transmembrane receptor composed of two alpha and two beta chains linked by disulfide bonds. INSRR shares high homology with the INS (IR) and the IGF-1R, but doesn't bind any of IR and IGF-1R known ligands. The antibody is specific to INSRR.
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for INSRR antibody 55112-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |