Speedy™ Human TNFSF18 One-Step ELISA Kit
Sensitivity
3.0 pg/mL
Range
39-2500 pg/mL
Reactivity
Human
Cat no : SE50206
Synonyms
Activation-inducible TNF-related ligand, AITRL, GITRL, Glucocorticoid-induced TNF-related ligand, hGITRL
Validation Data Gallery
Product Information
| Product name | Speedy™ Human TNFSF18 One-Step ELISA Kit |
| Tests | 1 X 96 well plate |
| Sample type | Serum, Plasma |
| Assay type | Sandwich |
| Sensitivity | 3.0 pg/mL |
| Range | 39-2500 pg/mL |
| Reactivity | Human |
| Tested applications | Sandwich ELISA |
| Gene ID (NCBI) | 8995 |
Recovery
| Sample Type | Average | Range |
|---|---|---|
| Human plasma | 84% | 72%-102% |
IntraAssay
| Sample | n | mean ( pg/mL) | SD | CV% |
|---|---|---|---|---|
| 1 | 8 | 1,290.2 | 85.3 | 6.6 |
| 2 | 8 | 318.9 | 20.1 | 6.3 |
| 3 | 8 | 178.5 | 13.6 | 7.6 |
InterAssay
| Sample | n | mean ( pg/mL) | SD | CV% |
|---|---|---|---|---|
| 1 | 16 | 1,342.1 | 108.8 | 8.1 |
| 2 | 16 | 335.6 | 27.2 | 8.1 |
| 3 | 16 | 185.5 | 14.2 | 7.7 |
Background Information
TNFSF18 is also named as Glucocorticoid-induced TNF-related ligand (hGITRL). GITR is a gene coding for a member of the TNF receptor superfamily. GITR activation by its ligand (GITRL) influences the activity of effector and regulatory T cells, thus participating in the development of immune response against tumours and infectious agents, as well as in autoimmune and inflammatory diseases. GITR-GITRL interactions co-stimulate both responder T-cell functions and the suppressive functions of TReg cells. GITRL is expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells.
Properties
| Storage Instructions | All the reagents are stored at 2-8℃ for 6 months or -20℃ for 12 months. Refer to the protocol for further storage instructions. |
| Synonyms | Activation-inducible TNF-related ligand, AITRL, GITRL, Glucocorticoid-induced TNF-related ligand, hGITRL |